Neuromyelitis Optica Spectrum Disorders: a definite case with Autoimmune Thyroiditis CASE REPORT
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چکیده
Case Report: A 24 year-old female was admitted due to a sudden painful hypovision in the left eye. The etiological investigation was negative but brain MRI showed T2 hyperintensity of the left optic nerve with gadolinium enhancement, but no signal changes in the brain parenchyma. Eleven years before, she had been diagnosed with autoimmune thyroiditis based on hypothyroid goiter with biopsy-proven chronic lymphocytic inflammation and positive thyroid-related antibodies. Two years after optical neuritis, she developed sensory complaints below a thoracic defined level. MRI revealed a diffuse T2 hyperintense area from D2 to D5. She tested positive for antibody anti-NMO/Aquaporin-4. One month later she had a new episode of left optic neuritis. With two optic neuritis and one longitudinally extensive myelitis, with positive serum test for NMO antibody, she was diagnosed with NMOSD with hypothyroidism and started Azathioprine.
منابع مشابه
Neuromyelitis optica (NMO) and autoimmune thyroiditis
Neuromyelitis optica (NMO or Devic's syndrome) is a rare demyelinating disease of the CNS that predominantly affects the spinal cord and optic nerves and shares many clinical and radiological features with multiple sclerosis (MS). The association of NMO with autoimmune thyroiditis has been reported very rarely. Early differentiation between NMO and MS is very important because they have differe...
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